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In mammals, vitamin B12 is needed as a coenzyme to the transmethylation of homocystine to methionine, in making use of 5-methyl-tetrahydrofolic acid, and from the conversion of methylmalonyl-CoA to succinyl-CoA (Weissbach and Taylor, 1970). The concentration of vitamin B12 needed within the diet plan in the rat may perhaps range with dietary conten